Zakiyatun Nisa Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia
Nawal Zuhdaniel Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia
Ardiman Hasudungan Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia
Dimas Prayogo Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia
Wanda Rhisma Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia
Mutia Meireni Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia
(1) Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia (2) Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia (3) Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia (4) Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia (5) Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia (6) Department of Physics, Faculty of Military Mathematics and Natural Sciences, Republic of Indonesia Defense University, Bogor, Indonesia (*) Corresponding Author
Abstract
The development of cyclotron technology in the healthcare industry became important after the production of several radioisotopes with short half-lives were used. Single Photon Emission Computed Tomography (SPECT) became one of the important diagnostic methods, especially in the visualization and functional analysis of internal organs. In Indonesia, cyclotron is only available in a few hospitals and is not fully optimized in the production of radionuclides for SPECT. By involving cyclotron technology in the production of radionuclides for SPECT, it is hoped that this research can make a contribution in advancing the field of nuclear medicine, opening up new opportunities for diagnostic research, and improving the healthcare quality by providing more accurate and timely information to medical practitioners. Relatively low-energy cyclotrons are required to produce PET radionuclides such as 18F, 11C, 13N, 64Cu, and 124I with energies between 2.7 and 5.6 MeV. Medium cyclotrons capable of accelerating protons greater than 10 MeV are required for the production of SPECT radionuclides such as 99mTc, 123I, 201Tl, 111In and 67Ga.
Keywords
Cyclotron; Nuclear Cross-section; Production Efficiency; Radionuclide Production;, Single Photon Emission Computed Tomography (SPECT)
Anum. (n.d.). Cyclotron: Definition, Principle, Construction, Working, and Uses.
Deconninck, G. (1978). Introduction to Radioanalytical Physics. https://doi.org/https://doi.org/10.1016/C2013-0-11877-6
Evans, R. D. (1955). THE ATOMIC NUCLEUS Radiative Collisions of Electrons ’with Atomic Nuclei (p. 600).
Guillaume, M., Lambrecht, R. M., & Wolf, A. P. (1975). Cyclotron production of 123Xe and high purity 123I: A comparison of tellurium targets. The International Journal Of Applied Radiation And Isotopes, 26(12), 703–707. https://doi.org/10.1016/0020-708X(75)90125-8
International Atomic Energy Agency. (2001). Charged particle cross-section database for medical radioisotope production: diagnostic radioisotopes and monitor reactions. Iaea-Tecdoc-1211, May, 292.
Kambali, I. (2019). Proton-produced radionuclides for radiodiagnostic modalities in cancer studies. Journal of Physics: Conference Series, 1153(1). https://doi.org/10.1088/1742-6596/1153/1/012106
Nuttens, V., Abs, M., Delvaux, J., Jongen, Y., Kleeven, W., Mehaudens, M., Romao, L. M., Servais, T., Vanderlinden, T., Ion, P. V., & Applications, B. (2010). CYCLOTRON VACUUM MODEL AND H- GAS STRIPPING LOSSES. 200–202.
Saktia, A. (2013). MENGENAL SIKLOTRON DAN PEMANFAATANNYA DI BIDANG MEDIS. NBER Working Papers, 89.
Weiner, R. E., & Thakur, M. L. (1995). Radionuclides: Applications in Diagnostic and Therapeutic Nuclear Medicine. Ract, 70–71(Supplement), 273–288. https://doi.org/10.1524/ract.1995.7071.special-issue.273
Refbacks
There are currently no refbacks.
Office Address: Faculty of Military Mathematics and Natural Sciences Republic of Indonesia Defense University Indonesian Peace and Security Center Complex, Sentul, Bogor 16810, Indonesia Email:munisi.unhanri@gmail.com | WhatsApp:+6285742313964
